Final answer:
The two factors that caused crops to stop growing in Sumer were poor drainage and salt deposits in the cultivated soil.
Step-by-step explanation:
The two factors that caused crops to stop growing in Sumer were poor drainage and salt deposits in the cultivated soil. The flooding of the Tigris and Euphrates rivers every year left behind dark, fertile soil, but also resulted in poor drainage and the accumulation of salt deposits, making the soil unsuitable for crops.
The cultivation of crops in flat plains isolated from trade routes did not directly cause the crops to stop growing, but it may have contributed to the lack of resources and support needed for successful farming.