Final answer:
Carbon monoxide affects the mitochondria by limiting oxygen transport, thereby disrupting ATP production as mitochondria are the cell's main ATP producers.
Step-by-step explanation:
Carbon monoxide indirectly affects the mitochondria of a cell. Since mitochondria are the "energy factories" of a cell, responsible for making adenosine triphosphate (ATP), any disruption of oxygen transport impacts their function. Carbon monoxide binds to hemoglobin with a higher affinity than oxygen, thus decreasing the oxygen supply available for the electron transport chain in mitochondria, which is crucial for ATP production. Therefore, the organelle that would be affected by carbon monoxide, as stated in the question, is option B. Mitochondria.