Question

A nurse is providing teaching to a ct who has a new prescription for nifedipine. Which of the following foods should the nurse instruct the ct to avoid?

a) High-calcium foods
b) Foods rich in vitamin K
c) Foods high in tyramine
d) Grapefruit or grapefruit juice

Answer 1

When taking nifedipine, it is important to avoid consuming grapefruit or grapefruit juice. Grapefruit contains substances that can interfere with the metabolism of nifedipine, leading to potential side effects and drug interactions. The nurse should instruct the patient to avoid grapefruit products and discuss any dietary concerns with their healthcare provider.

Step-by-step explanation:

When taking the medication nifedipine, it is important to avoid consuming grapefruit or grapefruit juice. This is because grapefruit contains substances that can interfere with the way the body metabolizes nifedipine, leading to higher levels of the medication in the bloodstream than intended. This can increase the risk of side effects and potentially harmful drug interactions.

Grapefruit can inhibit an enzyme called CYP3A4, which is responsible for breaking down nifedipine in the body. When this enzyme is inhibited, nifedipine can accumulate and reach toxic levels. Therefore, it is best to avoid consuming grapefruit or grapefruit juice while taking nifedipine.

It is important for the nurse to instruct the patient about this food-drug interaction and emphasize the need to avoid grapefruit products during their treatment with nifedipine. Other foods and drinks that may interact with nifedipine include alcohol and high-fat meals, so it is recommended to discuss with their healthcare provider about any dietary restrictions or concerns.