Final answer:
The most likely explanation for cell membrane asymmetry is that the two sides of a cell membrane face different environments and fulfill different functions, crucial for processes like tissue development and immune response.
Step-by-step explanation:
The cell membranes are asymmetrical primarily because the two sides of a cell membrane face different environments and carry out different functions. This asymmetry is essential for the diverse roles the membrane plays in cellular function, such as communication and selective transport. The inner and outer layers of the plasma membrane are composed of different sets of proteins and lipids that are adapted to the cell's internal environment and the extracellular space, respectively. For example, on the interior of the membrane, some proteins anchor the membrane to the cytoskeleton, while on the exterior, different proteins and carbohydrates play roles in cell-cell recognition and signaling. This functional differentiation is crucial for processes like tissue and organ formation and the immune system's ability to distinguish self from non-self.