Final answer:
The volume of air contained in the alveoli does not affect alveolar PO₂. Other factors such as the rate of oxygen consumption by tissues, alveolar ventilation, the PO₂ of inspired air, and the humidification of air as it moves through the conducting zone affect alveolar PO₂.
Step-by-step explanation:
The volume of air contained in the alveoli does NOT affect alveolar PO₂. Alveolar PO₂ is primarily affected by factors such as the rate of oxygen consumption by respiring tissues, alveolar ventilation, the PO₂ of inspired air, and the humidification of air as it moves through the conducting zone.