Question

An oncologist prescribes doxorubicin 60 mg/m2 iv every 21 days. how many ml need to be withdrawn from a 75 ml multi-dose vial with a reconstituted strength of 2 mg/ml for a female with a bsa of 1.8 m2?

Answer 1

To calculate the volume of doxorubicin needed from a 75 mL multi-dose vial, we can use the formula: Volume (mL) = Dose (mg/m2) x BSA (m2) / Concentration (mg/mL). Plugging in the given values, we find that 54 mL of doxorubicin needs to be withdrawn from the vial.

Step-by-step explanation:

To determine the volume of doxorubicin needed from a 75 mL multi-dose vial, we can use the formula:

Volume (mL) = Dose (mg/m2) x BSA (m2) / Concentration (mg/mL)

Given:

• Dose = 60 mg/m2
• BSA = 1.8 m2
• Concentration = 2 mg/mL

Plugging in these values, we get:

Volume (mL) = 60 mg/m2 x 1.8 m2 / 2 mg/mL = 54 mL

Therefore, 54 mL of doxorubicin needs to be withdrawn from the 75 mL multi-dose vial.