Final answer:
RNA and DNA sugars differ by the presence of a hydroxyl group at the 2' carbon in ribose (RNA) and the absence of it in deoxyribose (DNA).
Step-by-step explanation:
The sugars in RNA and DNA differ by a single hydroxyl group. The sugar in RNA is ribose, which has a hydroxyl group at the 2' carbon atom. In contrast, the sugar in DNA is deoxyribose, which has a hydrogen atom instead of a hydroxyl group at the 2' position. This difference is crucial for the structure and function of these molecules. Both DNA and RNA contain five-carbon sugars and are essential components of the genetic material in cells.