Final answer:
The Anti-Federalists argued for a strong national government and a bill of rights to protect individual liberties from potential government abuse.
Step-by-step explanation:
The Anti-Federalists' argument concerning the Constitution is that a strong national government is necessary. They believed that the power given to the federal government by the Constitution threatens the rights and liberties of ordinary citizens. They also insisted on having a bill of rights to protect individual liberties from potential government abuse. This argument was in contrast to the Federalists, who believed that the limited set of powers granted to Congress in the Constitution would be sufficient.