Final answer:
The wobble position of a codon is the 3' (third) base, which allows for base variability and is associated with the concept of wobble pairing between codons and anticodons, including those with inosine.
Step-by-step explanation:
The wobble position in a codon is the 3' (third) base. This position allows for variability in the third nucleotide of a codon without necessarily changing the amino acid that is translated. The idea of wobble pairing relates to the flexibility in the base-pairing rules, particularly between the codon and anticodon of mRNA and tRNA, respectively. This flexibility is due to the structure of the tRNA molecule and chemical properties of the bases. Additionally, some tRNAs contain the first anticodon nucleotide as inosine (I), which can base pair with three nucleotides: U, C, and A. As a result of this 'wobble,' a single tRNA can recognize multiple codons that differ in their third base, thus aiding in the efficiency and fidelity of protein translation.