Final answer:
The correct answer is approximately 33% (Option D) of affected males have X-linked recessive lethal disorders due to a new mutation, rather than inheritance from a carrier female.
Step-by-step explanation:
The question asks about the percentage of affected males with X-linked recessive lethal disorders that can be attributed to new mutations, rather than inheritance from a carrier female. This question pertains to the patterns of inheritance for X-linked recessive disorders. According to available resources, when considering Haldane's rule for X-linked recessive disorders, it is known that a mutation must arise de novo in a fraction of cases as females typically carry two X chromosomes and are less likely to be affected due to the presence of a second, usually functioning X chromosome.
In practice, this means that not all affected males inherit the mutation from their mother, who would be a carrier (having one normal and one mutated X chromosome). Some affected males will have the disorder due to a new mutation occurring in the X chromosome they receive from their mother. While the exact percentage can vary and might be difficult to pinpoint due to varying mutation rates across different genes and populations, historically, it has been estimated that about 33% (Option D) of all cases of hemophilia, a common X-linked recessive disorder, are caused by a new mutation.
Therefore, the correct answer to the question 'What approximate percentage of affected males is attributable to a new mutation in X-linked recessive lethal disorders?' would be 33% (Option D).