Final answer:
The sentence that is most likely a topic sentence is "First, consider the effects of calcium on the diet," as it introduces a discussion point that would typically be elaborated with details following the sentence.
Step-by-step explanation:
The sentence most likely to be a topic sentence and NOT a detail is "B. First, consider the effects of calcium on the diet." This statement broaches a new subject that can be followed by various supporting details and is therefore indicative of the main idea or topic of a paragraph. In comparison, the other sentences provide specifics that would support or explain a main idea.
Bone is the hardest connective tissue, providing protection to internal organs and supporting the body. The bone's extracellular matrix is comprised mostly of collagen fibers embedded in a mineralized ground substance with hydroxyapatite, a form of calcium phosphate, which helps to make bone hard and resistant to being brittle.
Bone's ability to recover from injuries swiftly, due to its vascular nature, is in contrast with cartilage, which does not heal as quickly because it is a less vascular type of connective tissue.