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Which class of antiarrhythmic medications includes Amiodarone, Dofetilide, and Ibutilide?

A. Sodium Channel Blockers.
B. Beta-Adrenergic Blockers.
C. Calcium Channel Blockers.
D. Potassium Channel Blockers.

User Choxmi
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1 Answer

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Final answer:

Amiodarone, Dofetilide, and Ibutilide are potassium Channel Blockers, used to treat cardiac dysrhythmias by impeding the flow of K+ ions and prolonging the repolarization phase of the cardiac action potential.

Step-by-step explanation:

The class of antiarrhythmic medications that include Amiodarone, Dofetilide, and Ibutilide is Potassium Channel Blockers. These medications are used to treat cardiac dysrhythmia, an abnormal electrical activity in the heart. They work by impeding the movement of potassium ions (K+) through voltage-gated potassium channels.

Specifically, in the action potential of cardiac cells, potassium channels are primarily responsible for the repolarization phase. Therefore, by blocking these channels, these medications prolong the repolarization phase, which can help to correct abnormal heart rhythms.