Final answer:
The principle of beneficence is the ethical principle listed that guides research involving animal subjects, ensuring their humane treatment and minimizing pain and distress.
Step-by-step explanation:
In the context of ethical principles guiding research with animal subjects, the principle of beneficence is the one listed.
This principle suggests researchers should act in ways that benefit the animals being used in research. In practice, this means designing studies where pain and distress are minimized, ensuring the research offers potential benefits, and treating all subjects ethically and humanely.
This adherence to beneficence in animal research requires the approval of an Institutional Animal Care and Use Committee (IACUC), and demands regular inspections to guarantee humane treatment of the animals.