Question

Choose the correct sequence leading to cortisol release. A.) CRH is secreted by the hypothalamus, CRH stimulates the pituitary gland with releases ACTH, ACTH stimulates the adrenal glands and cortisol is released into the blood stream. B.) ACTH is released by the hypothalamus, ACTH stimulates the pituitary to release CRH, CRH stimulates the adrenal glands to release cortisol into the bloodstream C.) Aldosterone stimulates the pituitary gland to release CRH, CRH stimulates the adrenal glands to release cortisol into the bloodstream. D.) CRH is secreted by the pituitary gland, CRH stimulates the hypothalamus to release ACTH, ACTH stimulates the adrenal glands to release cortisol into the bloodstream

Answer 1

The direct answer to the sequence leading to cortisol release is option A, where CRH from the hypothalamus stimulates the pituitary gland to release ACTH, subsequently inducing cortisol release from the adrenal glands.

Step-by-step explanation:

The correct sequence leading to cortisol release is outlined in option A: CRH is secreted by the hypothalamus, which then stimulates the pituitary gland to release ACTH, and finally, ACTH stimulates the adrenal glands to release cortisol into the bloodstream.

Corticotropin-releasing hormone (CRH), produced by the hypothalamus, initiates the hormonal cascade responsible for cortisol release. The anterior pituitary gland subsequently secretes adrenocorticotropic hormone (ACTH), which directs the adrenal cortex to produce cortisol. This process is part of the hypothalamic-pituitary-adrenal (HPA) axis, which is crucial in the body's response to stress. Moreover, cortisol itself provides a negative feedback mechanism to regulate this system and prevent the overproduction of these hormones.