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describe in detail the process of replication in DNA

User Flocked
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Answer:

DNA replication is a semi-convervative process, meaning that half of the original DNA strand will stay the same and it will make a new DNA strand. In DNA replication, there are two strands, one being the lagging and the other being the leading. The DNA helicase unravels the DNA's double helix, how? the DNA helicase interrupts the hydrogen bonds between the four bases, (A) Adenine, (T) Thymine, (C) Cytosine, and (G) Guanine. after the DNA helicase unravels the double helix, it will be formed in a Y like shape, that is known as the replication fork. After the first process, another enzyme, known as the DNA primase generates primers that bind the 3' end of the leading strand for replication. After this occurs, the DNA polymerases III adds new bases to our strand, this enzyme also checks for any mismatched pairs. DNA polymerases adds something called the okazaki fragments to our strands right in between our primers. Then comes along the exonuclease, this guy gets rid of all the RNA primers in our original strand and are replaced by other bases, while this happens, another one checks up on the new DNA. DNA ligase makes sure to unify one of the strands, by this we must link our okazaki fragments together using the DNA ligase. At last, the DNA replication is finished and we are now left with 2 DNA molecules, half original strand, half new strand.

User Mahmoud Metwally
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