Final answer:
The Pantheon in Rome, rebuilt by Hadrian, was not originally designed for Christian worship. It was intended as a dedication to all the gods of Rome and also signified imperial authority and the emperor's relationship to his predecessors.
Step-by-step explanation:
The Pantheon in Rome as rebuilt by Hadrian was not designed for Christian worship, which is the correct answer to the question: "Which of these is not a possible meaning of the Pantheon in Rome as rebuilt by Hadrian?"
The Pantheon was dedicated to all the gods of ancient Rome, signifying the Roman ambition to bring cosmos or order to the gods just as they brought foreign societies into political order. Its connection with the divine cosmos was demonstrated by the 28 coffers on the dome, a number of significant mystical and religious meaning in classical antiquity. Moreover, the Pantheon served to honor the emperor's relationship to his predecessors and reflected the imperial authority on earth as a reflection of the divine cosmos.
Despite the Pantheon being a center for worshipping all gods, and possibly being a dynastic sanctuary or even part of a ruler cult, and despite its later conversion to a church in the 7th century, it was originally not designed as a Christian worship place during Hadrian's time. It was a temple that was also aligned with Augustus's mausoleum, further underscoring its imperial connections.