Final answer:
This political cartoon illustrates the issue of American expansion and the disregard for non-interference in other countries and peace treaties.
Step-by-step explanation:
This political cartoon illustrates the issue of American expansion. The cartoon appears to be in favor of American expansion as it depicts Uncle Sam (symbolizing the United States) stepping over words such as 'non-interference in other countries' and 'peace treaties'.
These words represent the idea of respecting the sovereignty of other nations and maintaining peaceful relations. The cartoonist's message is that the United States is disregarding these principles in its pursuit of expansion.