Question

It might be better to characterize hormones by EC50 than by k d . Why? Choose the best answer. Equilibrium dissociation constant ke characterizes the binding of ligands, not of hormones Equilbrium between binding and dissociation may not be reached due to receptor endocytosis Dissociation constant ke has nothing to do with biological response

Answer 1

Hormones should be characterized by EC50 instead of kd because kd characterizes the binding of ligands, not hormones. Receptor endocytosis can prevent equilibrium between binding and dissociation from being reached. The dissociation constant kd is not related to the biological response of hormones.

Step-by-step explanation:

The reason it might be better to characterize hormones by EC50 than by kd is because the equilibrium dissociation constant kd characterizes the binding of ligands, not hormones.

Hormones can undergo receptor endocytosis, which may prevent equilibrium between binding and dissociation from being reached.

Additionally, the dissociation constant kd has nothing to do with the biological response of hormones.