Final answer:
The colonists who established the Plymouth Colony mainly wanted to avoid religious persecution and practice their religion freely.
Step-by-step explanation:
The colonists who established the Plymouth Colony mainly wanted to avoid religious persecution and practice their religion freely. The Pilgrims, who were separatists from the Church of England, sought a place where they could worship as they believed scripture demanded, separate from the corrupt Church of England. They formed the Plymouth Colony in present-day Massachusetts, where they established self-government and the Mayflower Compact.