Final answer:
Epigenetic markers on nuclear periphery are gene poor, compact, and involved in gene silencing through DNA methylation and histone modification.
Step-by-step explanation:
These are epigenetic markers that are gene poor, compact, and are involved in gene silencing. These markers are located on the nuclear periphery.
One mechanism of gene silencing involves DNA methylation and chemical modification of histone tails, which alter the spacing of nucleosomes and change gene expression. Highly methylated DNA regions with deacetylated histones are tightly coiled and transcriptionally inactive.