Final answer:
RNA polymerase I functions in the expression of 18S and 28S ribosomal genes and is largely localized to the nucleolar region of the nucleolus.
Step-by-step explanation:
The RNA polymerase that functions in the expression of 18S and 28S ribosomal genes and is largely localized to the nucleolar region of the nucleolus is RNA polymerase I.
RNA polymerase I is located in the nucleolus, where it transcribes, processes, and assembles ribosomal RNA (rRNA) into ribosomes. It synthesizes the 18S, 5.8S, and 28S rRNAs from the tandemly duplicated set of ribosomal genes.