Final answer:
The factors affecting a client's blood pressure include weight, age, gender, ethnicity, and hormones, which are all crucial to consider for accurate blood pressure assessment.
Step-by-step explanation:
When assessing a client's blood pressure, a nurse should recognize several factors that can affect the measurement. These factors include weight, age, gender, ethnicity, and hormones. Specifically, a 45-year-old male African-American client who weighs 110 kg could be more prone to hypertension due to the combined influence of these factors. Automatic blood pressure measurement devices more commonly used in hospitals can mitigate some variability caused by manual measurement techniques, but it is still important to consider these variables for an accurate assessment.