Question

What are the diverse ways in which TSG proteins function?

Answer 1

TSG proteins have diverse functions in cell growth, cell cycle regulation, cell death, genome stability, and tumor suppression.

Step-by-step explanation:

TSG proteins, also known as tumor suppressor genes, have diverse functions in various biological processes. Some of the diverse ways in which TSG proteins function include:

1. Regulation of cell growth and proliferation
2. Control of cell cycle progression
3. Induction of cell death (apoptosis)
4. Maintenance of genome stability
5. Suppression of tumor formation and progression

For example, the p53 protein, a well-known TSG, plays a crucial role in regulating cell cycle checkpoints and initiating apoptosis in response to DNA damage.

Another example is the BRCA1 protein, which is involved in DNA repair and suppression of breast and ovarian cancers.