Final answer:
High-energy compounds for substrate-level phosphorylation include 1,3-bisphosphoglycerate, phosphoenolpyruvate, and creatine phosphate. These compounds can donate high-energy phosphates to ADP, producing ATP.
Step-by-step explanation:
The compounds that can be used as high-energy compounds for substrate-level phosphorylation include 1,3-diphosphoglyceric acid (1,3-bisphosphoglycerate), phosphoenolpyruvate (PEP), and creatine phosphate. These compounds contain high-energy bonds, releasing sufficient free energy (a minimum of 7.4 Kcal/mol) during hydrolysis that can be utilized for the phosphorylation of ADP to ATP. Specifically, 1,3-bisphosphoglycerate is involved in glycolysis where it donates a phosphate group to ADP to form ATP, facilitated by the enzyme phosphoglycerate kinase.
Phosphoenolpyruvate is another key metabolite in glycolysis, which when converted to pyruvate by pyruvate kinase generates ATP from ADP. Creatine phosphate, while not directly involved in glycolysis, has a high-energy phosphate bond that can be used to regenerate ATP from ADP.