Question

The tissue specific histone binding enzymes that catalyze each chemical modification of histones are also attracted to the sites where the alteration has already occurred, thus catalyzing what?

Answer 1

Histone binding enzymes catalyze reversible changes to histone proteins and DNA, affecting chromatin conformation and gene transcription.

Step-by-step explanation:

The tissue specific histone binding enzymes catalyze chemical modifications of histones, which can attract these enzymes to the sites where the alteration has already occurred. This process catalyzes the reversible changes to histone proteins and DNA, such as acetylation, de-acetylation, methylation, and phosphorylation. These modifications affect how tightly wound the DNA is around the histone proteins, ultimately determining whether a chromosomal region is open or closed to gene transcription.