Question

What are the contradictions of Tamsulosin (Flomax)?

1) Hypersensitivity to tamsulosin or any component of the formulation
2) Concomitant use of strong CYP3A4 inhibitors
3) Severe hepatic impairment
4) D. Severe renal impairment
5) All of the above

Answer 1

Tamsulosin (Flomax) has several contradictions, including hypersensitivity to the medication or its components, concomitant use of strong CYP3A4 inhibitors, severe hepatic impairment, and severe renal impairment.

Step-by-step explanation:

Tamsulosin (Flomax) has several contradictions:

1. Hypersensitivity to tamsulosin or any component of the formulation: Some individuals may have an allergic reaction to tamsulosin or any of the ingredients in the medication.
2. Concomitant use of strong CYP3A4 inhibitors: Tamsulosin should not be taken with medications that are strong CYP3A4 inhibitors as it may lead to increased levels of tamsulosin in the body.
3. Severe hepatic impairment: Individuals with severe liver problems should avoid using tamsulosin as it may worsen their condition.
4. Severe renal impairment: Tamsulosin should also be avoided by individuals with severe kidney problems as it may not be properly eliminated from the body.