Final answer:
The CD8 T cell response can be generated through the cross-presentation pathway of antigen presentation, which is primarily a function of dendritic cells. This pathway is utilized when intracellular pathogens are phagocytosed but do not directly infect antigen-presenting cells.
Step-by-step explanation:
The CD8 T cell response can be generated via the cross-presentation pathway of antigen presentation.
Cross-presentation is a mechanism used by dendritic cells to present antigens on MHC I molecules to CD8 T cells.
This pathway is utilized when intracellular pathogens do not directly infect antigen-presenting cells, such as dendritic cells, but are instead phagocytosed.
The exact mechanisms of cross-presentation are still not fully understood.