Question

Because of the imprecision of molecular joining, recombination between LV and J regions shows considerable variation. Which additional circumstance contributes to this variation?

A) transmutation
B) hypermutation
C) transfection
D) conjugation
E) transduction

Answer 1

Hypermutation is the additional circumstance that contributes to the variation in the recombination of immunoglobulin genes during B cell maturation, enhancing the immune response.

Step-by-step explanation:

The question is regarding the variation in the recombination of immunoglobulin genes during B cell maturation. Other than the imprecision of molecular joining between V and J regions, hypermutation contributes to the variation seen in these recombinations. The mechanism of hypermutation introduces further diversity into the variable regions of antibodies after the initial recombination of V, D, and J segments, allowing for an enhanced adaptive immune response.