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What mechanism of nonreplicative transposition occurs in eukaryotes?

User Sandstrom
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The nonreplicative transposition in eukaryotes generally involves cut-and-paste transposition, where a transposon is excised and integrated into a new location without replication of the original element. This process, mediated by transposase, is important for creating genetic diversity and can be influenced by cellular stress.

Step-by-step explanation:

Mechanism of Nonreplicative Transposition in Eukaryotes

In eukaryotes, nonreplicative transposition typically occurs through a mechanism known as cut-and-paste transposition. This mechanism involves the excision of the transposon from its original location and subsequent integration into a new site within the genome, without creating a copy at the original site. The process is mediated by an enzyme called transposase, which recognizes specific sequences at the ends of the transposon. These mechanisms relate to how transposition can be triggered by cellular stress, and the transposon's ability to introduce genetic diversity is a reflection of its evolutionary significance.

Class II transposons, like other genetic elements, can induce genetic changes by altering the gene sequence upon insertion. The cut-and-paste process is contrasted with replicative transposition, where the original transposon remains in place while a new copy is inserted elsewhere. Important to note is the role of siRNAs in potentially regulating transposon activity and preventing uncontrolled transposition.

User Michalczukm
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