Final answer:
The correct statement about γδT cells and B-1 B cells is that both can self-renew in the periphery and do not need to be replenished from primary lymphoid tissues, and they do not require information from antigen-presenting cells (APCs) to become activated.
Step-by-step explanation:
Out of the provided options, the correct statement about γδT cells and B-1 B cells is:
D. Both A and D.
A. Both can self-renew in the periphery and do not need to be replenished from primary lymphoid tissues. Both γδT cells and B-1 B cells possess the ability to self-renew in the periphery, meaning they can survive and divide outside of primary lymphoid tissues like the bone marrow or thymus.
D. Both A and D. In addition to self-renewal, both γδT cells and B-1 B cells are part of the innate immune system and do not require information from antigen-presenting cells (APCs) to become activated.
Therefore, option D is the correct choice.