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Which of the following statements are TRUE about γδT cells and B-1 B cells?

A. Both can self-renew in the periphery and do not need to be replenished from primary lymphoid tissues.
B. Both have identical lymphocyte receptors to one another.
C. Both respond to their antigens via high-affinity receptor responses.
D. Both A and D
E. All of the above

User Dnsh
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Final answer:

The correct statement about γδT cells and B-1 B cells is that both can self-renew in the periphery and do not need to be replenished from primary lymphoid tissues, and they do not require information from antigen-presenting cells (APCs) to become activated.

Step-by-step explanation:

Out of the provided options, the correct statement about γδT cells and B-1 B cells is:
D. Both A and D.

A. Both can self-renew in the periphery and do not need to be replenished from primary lymphoid tissues. Both γδT cells and B-1 B cells possess the ability to self-renew in the periphery, meaning they can survive and divide outside of primary lymphoid tissues like the bone marrow or thymus.

D. Both A and D. In addition to self-renewal, both γδT cells and B-1 B cells are part of the innate immune system and do not require information from antigen-presenting cells (APCs) to become activated.

Therefore, option D is the correct choice.

User Triangle
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