Final answer:
The leading strand is synthesized continuously in the 5' to 3' direction, while the lagging strand is synthesized in fragments in the opposite direction of the replication fork. Hence, B) and D) are correct.
Step-by-step explanation:
The leading strand is synthesized continuously in the 5' to 3' direction, in the same direction as the replication fork. This strand is synthesized from the template strand that is oriented in the 3' to 5' direction.
On the other hand, the lagging strand is synthesized in short fragments called Okazaki fragments, in the opposite direction of the replication fork.
The Okazaki fragments require a primer to begin synthesis. The lagging strand is synthesized from the template strand that is oriented in the 5' to 3' direction.