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What are the four ways membrane proteins can associate with the lipid bilayer?

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Final answer:

Membrane proteins can associate with the lipid bilayer through integral proteins, peripheral proteins, phospholipids, and cholesterol.

Step-by-step explanation:

Membrane proteins can associate with the lipid bilayer in four ways:

  1. Integral proteins: These proteins are embedded within the hydrophobic interior of the bilayer and can transport materials in and out of the cell. For example, channel proteins selectively allow certain ions to pass through the membrane.
  2. Peripheral proteins: These proteins are loosely associated with the surface of the lipid bilayer. They play a role in enzymatic activity, structural support, and cell recognition.
  3. Phospholipids: These form the lipid bilayer and provide the structural foundation for the membrane.
  4. Cholesterol: Cholesterol molecules are interspersed within the lipid bilayer and can affect the fluidity and permeability of the membrane.

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