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Angiotensin I is formed from the plasma protein ____ by the action of the enzyme ____.

A. Angiotensin II; renin
B. angiotensinogen; ACE
C. angiotensinogen; renin
D. renin: ACE

1 Answer

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Final answer:

Angiotensin I is produced from angiotensinogen by the action of renin, and then it is converted to angiotensin II by ACE. This process is integral in regulating blood pressure and blood volume.

Step-by-step explanation:

Angiotensin I is formed from the plasma protein angiotensinogen by the action of the enzyme renin. Angiotensinogen is an inactive protein in the circulation produced by the liver; it is the precursor of angiotensin I. Renin is an enzyme secreted by the kidneys, specifically by the juxtaglomerular complex, in response to low blood volume or low sodium concentration. Once angiotensin I is produced, it is then converted into the active form, angiotensin II, by another enzyme known as angiotensin-converting enzyme (ACE), which is found in the lungs. Angiotensin II is a potent vasoconstrictor and stimulates the release of hormones aldosterone and antidiuretic hormone (ADH), both of which act to stabilize blood pressure and blood volume.

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