Final answer:
Individuals with a genetic incapability to repair UV-induced pyrimidine dimers may suffer from xeroderma pigmentosa, leading to DNA distortion and an increased risk of skin cancer.
Step-by-step explanation:
Individuals who are genetically incapable of repairing mutations caused by ultraviolet (UV) light, specifically pyrimidine dimers, are likely to suffer from a condition known as xeroderma pigmentosa. This condition makes one's skin highly sensitive to UV rays, leading to the formation of pyrimidine dimers, such as thymine dimers, in DNA.
Xeroderma pigmentosa patients have a defect in the nucleotide excision repair enzymes, which normally excise thymine dimers and correct the defect. As a result, affected individuals cannot repair these dimers, causing a distortion of the DNA structure and significantly increasing the risk of contracting skin cancer.