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Which of the following diseases had the highest mortality rate before vaccination became prevalent?

A. Smallpox.
B. Polio.
C. Measles.
D. Influenza.

User Latarsha
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1 Answer

5 votes

Final answer:

Smallpox had the highest mortality rate before vaccination became prevalent.

Step-by-step explanation:

The disease that had the highest mortality rate before vaccination became prevalent is Smallpox. Smallpox is caused by the variola major virus and historically had fatality rates of 50% or greater in susceptible populations. It was transmitted through inhalation of viral particles shed from lesions in the throat and spread systemically in the bloodstream, producing a pustular skin rash.

User Jeremy Boyd
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