Question

Which of the following statements about CCR5-delta32 allele is true?

A. It increases susceptibility to HIV infection.
B. It is associated with resistance to HIV infection.
C. It is linked to an increased risk of malaria.
D. It is a marker for Type 2 diabetes.

Answer 1

The CCR5-delta32 allele is associated with resistance to HIV infection.

Step-by-step explanation:

The statement that is true about the CCR5-delta32 allele is B. It is associated with resistance to HIV infection.

In individuals with the CCR5-delta32 mutation, the mutation leads to the production of a receptor that HIV cannot effectively bind to, thus blocking viral entry. People who are homozygous for this mutation have greatly reduced susceptibility to HIV infection, and those who are heterozygous have some protection from infection as well.