Final answer:
Dottie's constellation of symptoms corresponds to Parkinson's disease, which is a result of the loss of dopamine-producing neurons in the substantia nigra part of the brain.
Step-by-step explanation:
Dottie's symptoms of motor tremors, loss of balance, poor coordination, rigidity, and difficulty moving are indicative of Parkinson's disease, a neurodegenerative disease characterized by the degeneration of neurons that release dopamine. These neurons are located in the substantia nigra, a critical area of the brain for regulating movement. The loss of these neurons leads to distinct symptoms like a slow hunched shuffling walk, tremor, slowed movement, speech changes, and rigid muscles. Parkinson's disease may also have non-motor symptoms such as psychological issues, including dementia or emotional problems in its advanced stages.