Final answer:
The correct answer to the student's question is (1) fever, which is a systemic symptom of inflammation affecting the whole body.
Step-by-step explanation:
The student asks which item from the list provided is an example of a systematic symptom of inflammation. The correct answer is: 1) Fever. A fever is a systemic response to inflammation, where the body's temperature is elevated as part of the immune response. These systematic symptoms like fever, can influence the entire body, as opposed to local symptoms which would include redness and swelling at the site of inflammation.
Fever is specifically brought about by substances known as pyrogens that reset the body's thermostat in the hypothalamus. The four cardinal signs of inflammation recorded by Cornelius Celsus—redness, swelling, pain, and local heat—along with loss of function, on the other hand, are symptoms related to localized areas. The signs and symptoms of inflammation are important for identifying various conditions and initiating appropriate treatments.