Final answer:
The word 'fraud' in the excerpt from Literary Mysteries carries a strong negative connotation, casting doubt on Shakespeare's authorship.
Step-by-step explanation:
The excerpt from Literary Mysteries contains a statement that questions the authorship of Shakespeare's plays, suggesting that Francis Bacon may be the true writer. Among the choices provided, the word "fraud" carries a particularly strong negative connotation, suggesting deceit and criminal deception. This term stands out as the most negatively charged in the context of the allegation that William Shakespeare was not the actual author of the plays attributed to him, thereby undermining his credibility and legitimacy as a playwright.