Final answer:
Proofreading, mismatch repair, and excision repair are mechanisms that ensure DNA sequence accuracy. Hence the correct answer is option E
Step-by-step explanation:
The mechanism that ensures the DNA sequence in the genome remains accurate is proofreading during DNA replication. DNA polymerases have the ability to read the newly added base and ensure its complementarity with the template strand before adding the next base. If an incorrect base is added, the enzyme cuts it and replaces it with the correct base.
Another mechanism that helps maintain DNA sequence accuracy is mismatch repair. After DNA replication, mismatch repair enzymes detect and remove incorrectly added nucleotides, and replace them with the correct bases.
In addition to proofreading and mismatch repair, excision repair is another mechanism that ensures DNA sequence accuracy. It specifically repairs thymine dimers caused by UV exposure. The enzymes recognize and excise the damaged DNA, which is then replaced with the correct sequence.
Therefore, the correct answer to the question is all of the choices are correct.
Hence the correct answer is option E