Final answer:
Homo sapiens migrated out of Africa during the Quaternary (Pleistocene) period, interbred with Neanderthals, and settled in various regions globally, completing their massive emigration by about 40,000 years ago.
Step-by-step explanation:
Homo sapiens migrated outside of Africa during the Quaternary (Pleistocene) period. This era is known for its ice ages and was a time when early humans, including Homo sapiens, were able to spread out and populate different parts of the globe due to lower sea levels allowing for more passage through interior coastal routes. These migrations led to significant anthropological events, such as the interbreeding with Neanderthals and the settlement of lands across the Eurasian continents. By about 40,000 years ago, the massive global emigration of Homo sapiens was largely complete, with the exception of the Americas, which took until about 12,000 years ago when humans traveled overland on the Bering Land Bridge to arrive in the Americas.
The correct answer to the question, 'In what era did homo sapiens migrate outside of Africa?' is option b. Quaternary (Pleistocene).