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Explain intermolecular dehydration ether synthesis. Draw mechanism.

User Shams Reza
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Final Answer:

Intermolecular dehydration ether synthesis involves the reaction between two alcohol molecules, where one alcohol molecule undergoes deprotonation to form an alkoxide ion. This ion then attacks another alcohol molecule, leading to the elimination of water and the formation of an ether.

Step-by-step explanation:

Intermolecular dehydration ether synthesis occurs through an acid-catalyzed reaction. In this process, an alcohol molecule (R-OH) undergoes deprotonation to form an alkoxide ion (R-O^-). This deprotonation is catalyzed by an acid, commonly sulfuric acid (H2SO4). The acid donates a proton (H^+) to the hydroxyl group of the alcohol, converting it into water (H2O) and generating the alkoxide ion.

Subsequently, the alkoxide ion acts as a nucleophile and attacks another alcohol molecule, specifically at the electrophilic carbon attached to the hydroxyl group. This attack leads to the elimination of a molecule of water from the system. The resulting intermediate compound undergoes protonation by the acidic medium, regenerating the catalyst and forming the desired ether molecule.

The overall reaction mechanism involves the initial deprotonation step, followed by nucleophilic attack and elimination of water. The acid catalyst facilitates the reaction by providing the necessary conditions for deprotonation and protonation steps while not directly participating in the overall stoichiometry of the reaction.

It's crucial to note that the choice of reactants and conditions, such as the nature of the alcohol used, the strength of the acid catalyst, and temperature, significantly influences the efficiency and selectivity of this intermolecular dehydration process in producing ether compounds.

Explain intermolecular dehydration ether synthesis. Draw mechanism.-example-1
User Roberto Bisello
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