Question

In neuromuscular transmission, which ion responsible for facilitating the fusion of acetylcholine (ACH) containing vesicles with the presynaptic membrane of the axon terminal resulting in the release of ACH into the neuromusclular cleft

Answer 1

Calcium ions (Ca²+) facilitate the fusion of acetylcholine (ACh) containing vesicles with the presynaptic membrane in neuromuscular transmission.

Step-by-step explanation:

In neuromuscular transmission, the ion responsible for facilitating the fusion of acetylcholine (ACh) containing vesicles with the presynaptic membrane is calcium (Ca²+). When an action potential reaches the axon terminal, voltage-gated Ca²+ channels open, allowing Ca²+ ions to enter the cell. The influx of Ca²+ ions triggers the fusion of the vesicles with the presynaptic membrane, leading to the release of ACh into the neuromuscular cleft through exocytosis.