Final answer:
Hypophosphatemic Rickets is characterized by increased serum alkaline phosphatase levels, potentially normal or decreased serum calcium levels due to secondary hyperparathyroidism, decreased serum phosphorus levels, and increased serum parathyroid hormone levels.
Step-by-step explanation:
Hypophosphatemic Rickets is a specific form of rickets that particularly affects the metabolism of phosphorus. Lab findings typically include a series of characteristic changes:
- Increased serum alkaline phosphatase levels: This enzyme activity is typically elevated due to increased bone turnover.
- Decreased serum calcium levels are common; however, they may also be normal due to secondary hyperparathyroidism attempting to compensate for the low phosphorus.
- Decreased serum phosphorus levels: This is a hallmark of the disease, as renal losses of phosphate are a primary issue.
- Increased serum parathyroid hormone levels: This occurs as a response to hypophosphatemia and often coincides with compensatory mechanisms aimed at normalizing serum calcium levels.
In the context of Hypophosphatemic Rickets, which is sometimes referred to as vitamin D resistant rickets, these lab findings help in diagnosing the condition and reflect the disturbances in calcium and phosphorus metabolism that define the disease.