Final answer:
The prefrontal cortex is the most active brain region when people remember information about themselves, with the left inferior region engaged during semantic tasks and the right during information retrieval. The amygdala, hippocampus, and cerebellum also play crucial roles in memory processing and storage.
Step-by-step explanation:
When people remember information about themselves, the brain region that is most active is the prefrontal cortex. This area is associated with various functions, including processing self-referential information. Research has shown that specific tasks related to self-reference and semantic processing engage the left inferior prefrontal cortex, while retrieval of information activates the right frontal region. Memories are not found in one specific area but are distributed throughout the brain, with the amygdala, hippocampus, and cerebellum playing significant roles in processing and storing different types of memories. Semantic networks and associated memories are activated through a process called spreading activation, enhancing the recall of linked concepts.