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Ddx if misxing corrects?

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Final Answer:

The differential diagnoses if mixing corrects in the context of hematology include hemophilia, DIC (Disseminated Intravascular Coagulation), VWD (Von Willebrand Disease), and vitamin K deficiency.

Step-by-step explanation:

When assessing blood clotting issues, the "mixing study" evaluates if a coagulation factor deficiency is present. If correction occurs upon mixing the patient's plasma with normal plasma, conditions like hemophilia, DIC, VWD, or vitamin K deficiency are considered.

Hemophilia, an inherited clotting factor deficiency, can exhibit a correction upon mixing due to the addition of the deficient factor in normal plasma. DIC, a condition causing widespread clotting and bleeding, might show improvement due to dilution of abnormal factors. Von Willebrand Disease, characterized by a deficiency in von Willebrand factor, and vitamin K deficiency affecting clotting factor synthesis, can both show improvement upon mixing due to the addition of necessary factors.

Correct Answer: Hemophilia, DIC, VWD, Vitamin K deficiency

This is a flashcard question related to Onlinemeded Hematology.

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