Final answer:
DNA polymerase III and DNA polymerase alpha are the two proteins that do NOT have similar functions in prokaryotes and eukaryotes.
Step-by-step explanation:
Out of the given options, DNA polymerase III and DNA polymerase alpha are the two proteins that do NOT have similar functions in prokaryotes and eukaryotes. In prokaryotes, DNA polymerase III is the main replication enzyme responsible for synthesizing new DNA strands, while DNA polymerase alpha is involved in DNA replication in eukaryotes. These two enzymes differ in their structure, function, and involvement in DNA replication.