Question

The active form of a monomeric GTP-binding protein is the Choose one:

A. guanine nucleotide exchange factor (GEF).
B. GTPase-activating protein (GAP).
C. GTP-bound form.
D. GDP-bound form.

Answer 1

The active form of a monomeric GTP-binding protein is the GTP-bound form, which occurs when GTP is exchanged for GDP upon the activation of the protein by a signaling molecule binding to its receptor.

Step-by-step explanation:

The active form of a monomeric GTP-binding protein is the GTP-bound form. GTP-binding proteins, also known as G-proteins, play a key role in cell signaling. When a signaling molecule binds to the G-protein-coupled receptor, it causes the alpha subunit of the G protein to exchange GDP for GTP, thereby activating the protein. Activated G-proteins can then interact with other proteins or effectors, leading to a cascade of cellular responses. Once GTP is hydrolyzed back to GDP by the intrinsic GTPase activity of the G-protein, the protein becomes inactive again. Therefore, the correct answer is C. GTP-bound form.