Final answer:
After RAB-GTP and the tethering protein bind to the targeted membrane, the V-SNARE on the vesicle binds to the complementary T-SNARE on the target membrane, leading to membrane fusion and content delivery.
Step-by-step explanation:
Once RAB-GTP and the tethering protein bind, and are brought to the targeted membrane, several events ensue in the vesicle transport process. Notably, after RAB-GTP binds to the membrane, which is already attached to the tethering protein, the next step involves the V-SNARE and T-SNARE proteins. V-SNARE proteins located on the vesicle surface bind to complementary T-SNARE proteins on the target membrane. This inter-SNARE complex formation pulls the two membranes close together, leading to membrane fusion. Consequently, the contents of the vesicle are delivered to the inside of the target compartment or membrane. This series of events is critical for maintaining the proper functioning of various cellular processes such as secretion, membrane expansion, and organelle biogenesis.