Question

For each of the following sequences, rank them in order (from best to worst) as sequences that could be used to initiate translation according to Kozak's rules.

A. GACGCCAUGG
B. GCCUCCAUGC
C. GCCAUCAAGG
D. GCCACCAUGG

Answer 1

The sequences ranked in order based on Kozak's rules for translation initiation were: A. GACGCCAUGG, B. GCCUCCAUGC, C. GCCAUCAAGG, D. GCCACCAUGG.

Step-by-step explanation:

In order to rank the sequences according to Kozak's rules for translation initiation, we need to analyze each sequence and determine how closely it matches the consensus sequence 5'-gccRccAUGG-3'.

A. GACGCCAUGG - This sequence matches the consensus sequence exactly and would be ranked the highest.

B. GCCUCCAUGC - This sequence differs at one position (R is U instead of A or G) and would be ranked second.

C. GCCAUCAAGG - This sequence differs at two positions (R is U instead of A or G, and G is A instead of G or C) and would be ranked third.

D. GCCACCAUGG - This sequence differs at one position (G is A instead of G or C) and would be ranked fourth.